The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (NhpKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor ...
Cat # 11532610
100 µL
Cat # 11505041
100 µL
Cat # 11508261
200 µL
Cat # 10742155
100 µL
Cat # 11575081
100 µL
Cat # 17146613
100 µL
Cat # 11549521
100 µL
Cat # 15943834
100 µg
Cat # 15388641
100 µL
Cat # 15904645
100 µg
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